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A newly refined method for measuring the Pace of Aging in population-based studies provides a powerful tool for predicting risks associated with aging, including chronic illness, cognitive impairment, disability, and mortality. The method offers researchers and policy makers a novel approach to quantify how quickly individuals and populations experience age-related health decline.

The body defends itself against pathogens by depriving them of vital iron. However, this strategy doesn't always succeed against Salmonella. Researchers have discovered that these bacteria specifically target iron-rich regions within immune cells to replicate. Their findings on how pathogens evade the immune defense are important for fighting infections.

New research sheds light on an understudied area of science: iron levels in the blood and their relationship to cognitive performance in women transitioning into menopause. The findings are good news for women experiencing brain fog and other symptoms.

Researchers find that certain antioxidant enzymes, called selenoproteins, significantly contribute to fighting cell aging. The team used a gene knockout mouse model to help them study the effects of disrupting selenoprotein synthesis. This knockout negatively impacted hematopoietic stem cells and B cell-lineage immune cells, which was driven by the lack of selenoprotein-mediated fighting of lipid peroxides. These phenotypes mimic what is observed in age-related diseases, emphasizing the importance of selenoproteins in these disorders.

Maternal vitamin D levels in the first trimester were related to both prenatal growth and pregnancy outcomes, according to a new study. Low vitamin D levels during the first trimester of pregnancy were associated with higher rates of preterm birth and decreased fetal length.

A major trial has found a single iron infusion in the third trimester can significantly reduce anaemia in pregnant women and outperform the efficacy of iron tablets -- the current recommended standard of care.

A laboratory study provides evidence about how advanced age can be protective against cancer -- with implications for treating patients in different age groups.

Researchers have shown that over 80 percent of women are iron deficient by their third trimester. The findings raise concerns as the participants in the study were a low-risk and generally healthy cohort.

Antioxidant content and activity are increased during the processing and digestion of Japanese apricots pickled with salted red perilla leaves, new research shows.

Researchers found that a medicine called ferric carboxymaltose given in drip through the vein works faster and better than an iron tablet taken by mouth for the treatment of anaemia -- and it is as safe as the tablet.

Over half of people with iron deficiency were found to still have low iron levels three years after diagnosis, and among patients whose condition was effectively treated within that timeframe, they faced longer-than-expected delays, pointing to substantial gaps in appropriate recognition and efficient treatment of the condition, according to a new study.

Higher intake of heme iron, the type found in red meat and other animal products -- as opposed to non-heme iron, found mostly in plant-based foods -- was associated with a higher risk of developing type 2 diabetes (T2D) in a new study. While the link between heme iron and T2D has been reported previously, the study's findings more clearly establish and explain the link.

Doctors recommend making fruits and vegetables a foundational part of the treatment of patients with hypertension. Diets high in fruits and vegetables are found to lower blood pressure, reduce cardiovascular risk, and improve kidney health due to their base-producing effects. A new study details the findings from a five-year interventional randomized control trial.

Cell damage from oxidative stress is a major underlying cause of age-related cognitive and muscle strength decline. Antioxidants can reduce oxidative stress and prevent age-related health decline. A new study has found that mice administered with a blended antioxidant supplement show significant improvements in spatial cognition, short-term memory, and mitigated age-related muscle decline. The study suggests that blended antioxidant supplements hold promise as a dietary intervention for health issues associated with aging.

A new study finds a complex interplay between diet, genes, and the gut microbiota that could explain why IBD develops.

Our eating habits in industrialized societies are far removed from those of ancient humans. This is impacting our intestinal flora, it seems, as newly discovered cellulose degrading bacteria are being lost from the human gut microbiome, especially in industrial societies.

Natural products have unique chemical structures and biological activities and can play a pivotal role in advancing pharmaceutical science. In a pioneering study, researchers discovered Inaoside A, an antioxidant derived from Laetiporus cremeiporus mushrooms. This breakthrough sheds light on the potential of mushrooms as a source of therapeutic bioactive compounds.

Participants in the Framingham Heart Study who achieved higher levels of education tended to age more slowly and went on to live longer lives as compared to those who did not achieve upward educational mobility.

Scientists have discovered how mitochondria sense and control their glutathione levels, an antioxidant produced throughout the body. The first nutrient-sensing mechanism identified for an organelle, the finding has great translational potential.  

Health professionals have long praised the benefits of insoluble fiber for bowel regularity and overall health. New research suggests even more reasons we should be prioritizing fiber in our regular diets. Researchers found that each plant source of insoluble fiber contains unique bioactives -- compounds that have been linked to lower incidence of cardiovascular disease, cancer and Type 2 diabetes -- offering potential health benefits beyond those of the fiber itself. 

Researchers have shown in a mouse model and lab cultures that a compound derived from hops reduces the abundance of a gut bacterium associated with metabolic syndrome.

Blending certain ingredients in fruit smoothies can influence whether your body is getting a nutritional boost, finds a new study.

New research describes a fiber optic smart pant that can monitor movement and health. The pants can be used to detect activities such as sitting, squatting, walking or kicking without inhibiting natural movements.

A new study in Science Advances adds weight to a growing body of evidence that iron dysregulation may play an important role in Alzheimer's disease and therefore might provide a better target for treatments than amyloid beta plaques.

Researchers have made a landmark discovery linking iron regulation to a rare blood cancer has led to clinical trials of a potential new treatment for patients with the incurable disease.

In a first of its kind randomized controlled trial an international team of researchers shows that caloric restriction can slow the pace of aging in healthy adults. The CALERIE™ intervention slowed pace of aging measured from participants' blood DNA methylation using the algorithm DunedinPACE (Pace of Aging, Computed from the Epigenome). The intervention effect on DunedinPACE represented a 2-3 percent slowing in the pace of aging, which in other studies translates to a 10-15 percent reduction in mortality risk, an effect similar to a smoking cessation intervention.

The health-benefits of brown rice are well-known and widely advertised. But what exactly confers these excellent properties has been subject to speculation until now. Researchers have recently identified cycloartenyl ferulate (CAF) as the main antioxidant and cytoprotective constituent of brown rice. CAF can protect cells from stress directly through antioxidant effects and indirectly by boosting the production of antioxidants within cells.

Researchers have found new evidence that vitamin D may be metabolized differently in people with an elevated body mass index (BMI). The study is a new analysis of data from the VITAL trial, a large nationwide clinical trial that investigated whether taking vitamin D or marine omega-3 supplements could reduce the risk of developing cancer, heart disease, or stroke.

Researchers have developed a new way to fortify foods with vitamin A, which they hope could help to improve the health of millions of people around the world. In a new study, they showed that encapsulating vitamin A in a protective polymer prevents the nutrient from being broken down during cooking or storage.

Iron is a critical micronutrient for the survival of plants and humans, yet too much iron can also be toxic. An interdisciplinary research team has discovered that the protein PATELLIN2 is not only involved in regulating iron levels in plants. PATELLIN2 is one of a group of proteins that are also involved in the transport of vitamin E in humans. The results are also important for supplying people with iron via plant foods.

The availability of foods based on plant proteins to substitute for meat has increased dramatically as more people choose a plant-based diet. At the same time, there are many challenges regarding the nutritional value of these products. A study now shows that many of the meat substitutes sold in Sweden claim a high content of iron -- but in a form that cannot be absorbed by the body.

Two proteins ensure that cells can take up iron when needed. If both control proteins are switched off in mice, the animals develop severe anemia, as expected. Surprisingly, at the same time a cell type of the innate immune defense, the neutrophils, also dramatically decreases. Iron deficiency, a known defense mechanism against infectious pathogens, is a double edged sword, as it simultaneously curbs the defensive power of an important arm of the innate immune system.

Cystic fibrosis patients who supplement their diet with vitamin C can also derive greater benefit from another antioxidant, vitamin E, resulting in a reduction in damaging inflammation, a study suggests.

Research has found diets rich in highly refined fiber like inulin may increase the risk of liver cancer, particularly in individuals who have a vascular deformity in which blood from the intestines bypasses the liver. The discovery could help clinicians identify people who are at higher risk of liver cancer years in advance of any tumors forming and potentially enable individuals to reduce that risk through simple dietary modifications.

A research team has developed a high-resolution holographic endoscope system thinner than an injection needle for microscopic imaging inside a curved passage.

Researchers report on a novel function of vitamin K, which is generally known for its importance in blood clotting. The researchers discovered that the fully reduced form of vitamin K acts as an antioxidant efficiently inhibiting ferroptotic cell death.

The benefit of dietary fiber isn't just the easier pooping that advertisers tout. Fermentable fiber is an essential source of nutrients that your gut microbes and cells of the intestines need to stay healthy. Study participants who had been eating the least amount of fiber before being fed three different kinds of fiber supplement showed the greatest benefit from supplements, regardless of which ones they consumed.

Machine learning is playing an ever-increasing role in biomedical research. Scientists have now developed a new method of using molecular data to extract subtypes of illnesses. In the future, this method can help to support the study of larger patient groups.

Healthy adults who eat a diverse diet with at least 8-10 grams of soluble fiber a day have fewer antibiotic-resistant microbes in their guts, according to a new study. The results lead directly to the idea that modifying the diet has the potential to be a new weapon in the fight against antimicrobial resistance. And this does not require eating some exotic diet, but eating a diverse diet, adequate in fiber, a diet that some Americans already eat.

The health benefits of dietary fiber vary across individuals and may depend on the specific type of fiber and the dose consumed, researchers report.

A new article finds a strong link between the actions of free radicals and free iron in the skin -- a link that causes skin to age prematurely after exposure to the sun. The researchers have also identified antioxidants that can be added to skin products to mop-up the harmful iron, thereby minimizing sun damage.

Researchers have discovered a potential biomarker for Alzheimer's disease diagnosis that may also serve as a therapeutic target. Examining cerebrospinal fluid samples from patients with cognitive impairment ranging from subjective impairment to a diagnosis of Alzheimer's disease, they found a shift in the profile of specialized liquid mediators from pro-resolving to pro-inflammatory.

Researchers evaluated whether dietary fiber intake was associated with a decrease in inflammation in older adults and if fiber was inversely related to cardiovascular disease. The results showed that total fiber, and more specifically cereal fiber but not fruit or vegetable fiber, was consistently associated with lower inflammation and lower CVD incidence. Until now there had been limited data on the link between fiber and inflammation among older adults, who have higher levels of inflammation compared with younger adults.

Researchers have developed a new acoustic fabric converts audible sounds into electrical signals. They designed a fabric that works like a microphone, converting sound first into mechanical vibrations, then into electrical signals, similarly to how our ears hear.

The effect of iron supplementation on skeletal muscle atrophy in cancer patients and sufferers from other wasting diseases has been investigated by scientists who studied causes of these conditions in humans and mouse models. The findings shed light on wasting mechanisms in advanced stage cancer patients, for whom prevalence of devastating skeletal muscle atrophy known generally as cachexia reaches 80 percent.

Researchers found that higher levels of dietary fiber are associated with a reduced risk of developing dementia. In a large-scale study, over 3500 Japanese adults completed a dietary survey and were then followed up for two decades. Adults who consumed more fiber, particularly soluble fiber, were less likely to go on to develop dementia. These findings may relate to interactions between the gut and the brain.

Researchers developed a new blood test to measure the pace of biological aging. Based on an analysis of chemical tags on the DNA contained in white blood cells, called DNA methylation marks, the new test is named DunedinPACE (Pace of Aging Computed from the Epigenome). DunedinPACE is a new addition to a fast-growing list of DNA methylation tests designed to measure aging and contributes value-added over and above the current state of the art.

Regularly eating a small serving of dried goji berries may provide protection against age-related macular degeneration, the leading cause of vision loss in seniors.

A trial found that taking a much higher dose of vitamin D than recommended for five years did not affect total mortality or the incidence of cardiovascular disease or cancer in older men and women.

Patients hospitalized with COVID-19 had significantly increased levels of oxidative stress and oxidant damage, and markedly reduced levels of glutathione, the most abundant physiological antioxidant, according to a new study.

Approximately 10% of new coronary heart disease cases occurring within a decade of middle age could be avoided by preventing iron deficiency, suggests a new study.

Half of pregnant women who had a simple blood test to check their iron stores had low iron levels, and one in four had severe iron deficiency, according to a new article. But despite how common iron deficiency is, 40% of pregnant women in this large regional study never had their iron levels checked, and women of lower socioeconomic status were less likely to get tested. Researchers said the findings underscore the need to revisit clinical guidelines to ensure that ferritin testing, the standard measure of iron deficiency, is included as a routine part of maternal care and pregnancy health screenings.

Review of a landmark, 1944 study on adequate vitamin C levels leads researchers to challenge the WHO's recommended daily amounts.

Researchers say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals. Their experiments working with mice and fruit flies, however, found that the gene for CaMKII also contributes to an evolutionary tradeoff: increased susceptibility to age-associated diseases, frailty and mortality.

A diet rich in fermented foods enhances the diversity of gut microbes and decreases molecular signs of inflammation, according to researchers.

Research suggests a pair of compounds originating from hops can help thwart a dangerous buildup of fat in the liver known as hepatic steatosis.

Chronic exposure to second-hand smoke results in lower body weight and cognitive impairments that more profoundly affects males, according to new research in mice. The research examined daily exposure of 62 mice over a period of 10 months. Researchers used a specially designed 'smoking robot' that went through a pack of cigarettes a day in ventilated laboratory space. The longest previous study of this kind lasted three months.

Over the years, physicians and historians have attributed Shackleton's failing health during his Antarctic expeditions to scurvy or a congenital heart defect. By studying other explorers and learning they had symptoms comparable to those of Shackleton, researchers concluded that beriberi provided a sound scientific and medical explanation for the famed explorer's health struggles.

In a number of biological processes, iron-sulfur clusters play a vital role, where they act as cofactors to enzymes. Research now shows that cubic clusters can support unusual bonding states. This study shows that the cluster copes well with a multiple bond between iron and nitrogen -- a structural motif that may be involved in biological nitrogen fixation.

GlyNAC - a combination precursors of the natural antioxidant glutathione - improved many age-associated defects in older humans boosting muscle strength and cognition.

An analysis of data from a national health survey conducted before the pandemic found that pizza, soup and chicken are some of the main sources of sodium (salt) intake for people in all racial and ethnic groups. The study also showed clear differences among adults based on race and ethnicity.

Sterols are among the most abundant lipids in eukaryotic cells, yet are synthesized through notoriously long, complex metabolic pathways. Researchers have used a novel approach to show how they interact with other lipids that help cells self-organize.

The skin microbiome plays an important role in health and disease. Researchers have now substantiated that certain skin bacteria can protect us from the sun's ultraviolet (UV) radiation specifically by metabolizing cis-urocanic acid using an enzyme called urocanase. This enables the skin's ability to fine-tune how it responds to UV radiation. The findings demonstrate the ability of the skin microbiome to remodel host immune functions.

New research shows that regular exercise can help maintain Vitamin D levels during the darker months.

Climate scientists reveal that millions of today's young people will live through unprecedented lifetime exposure to heatwaves, crop failures, river floods, droughts, wildfires and tropical storms under current climate policies. If global temperatures rise by 3.5 C by 2100, 92% of children born in 2020 will experience unprecedented heatwave exposure over their lifetime, affecting 111 million children. Meeting the Paris Agreement's 1.5 C target could protect 49 million children from this risk. This is only for one birth year; when instead taking into account all children who are between 5 and 18 years old today, this adds up to 1.5 billion children affected under a 3.5 C scenario, and with 654 million children that can be protected by remaining under the 1.5 C threshold.

Scientists have developed a new type of handheld multi-purpose radiation detector that comprehensively detects all types of ionizing radiation. The device can be used by industrial and medical radiation users, regulatory authorities, the nuclear energy industry, first responders and military users. The technology has been patented and is currently being explored for commercialization.

Drawing inspiration from the tardigrade, researchers developed a new strategy that may protect cancer patients from the side effects of radiation therapy.

Because almost no existing programs focus specifically on reducing ultra-processed food (UPF) intake, researchers recently designed an intervention that included a variety of tactics to target the uniquely problematic aspects of UPFs. On average, participants successfully reduced their UPF intake by almost half.

Getting at least 30 minutes of daily summer sun in the first year of life may mean a lower relapse risk for children who are diagnosed with multiple sclerosis (MS) later, according to a new study. The study also found if a child's biological mother had at least 30 minutes of daily sun during the second trimester of pregnancy, the child had a lower risk of MS relapses. The study does not prove that sun lowers relapse risk for children with MS, it only shows an association.

Psoriasis is a chronic skin disease that manifests itself mainly with skin symptoms (dryness, itching, scaly skin, abnormal patches and plaques). It affects about 2% of the population and is mediated by an altered immune system response that triggers the proliferation of skin cells. Depending on the severity, there are different therapeutic options (topical medications, phototherapy, systemic drugs, etc.), but some conventional treatments can have harmful effects on patients.

Maternal vitamin D levels in the first trimester were related to both prenatal growth and pregnancy outcomes, according to a new study. Low vitamin D levels during the first trimester of pregnancy were associated with higher rates of preterm birth and decreased fetal length.

Researchers have combined injections of a novel hydrogel with systemic osteoporosis drugs in rats, achieving rapid local increases in bone density. The results offer hope for future fracture prevention therapies in osteoporosis patients.

A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts about 1 million people and kills about 30,000 people around the world every year.

With the help of an AI tool, computed tomography (CT) scans taken originally to look for tumors or bleeding or infections, also revealed calcium buildup in arteries, a sign of worsening cardiovascular disease.

Using significantly higher doses of vitamin D than recommended for five years did not affect the incidence of type 2 diabetes in elderly men and women, according to a new study.

In June of 2024, the Endocrine Society, influenced by a substantial body of research conducted in recent years, published new clinical practice guidelines for the testing and supplementation of Vitamin D for the prevention of disease. These new recommendations included limiting vitamin D supplementation beyond the daily recommended intake to specific risk groups and advised against routine 25-hydroxyvitamin D [25(OH)D] testing in healthy individuals.

A randomized, phase 2 clinical trial shows that adding high-dose, intravenous (IV) vitamin C to chemotherapy doubles the overall survival of patients with late-stage metastatic pancreatic cancer from eight months to 16 months. The finding adds to mounting evidence of the benefits of high-dose, IV vitamin C in treating cancer.

Researchers have developed a non-invasive, low-cost tool for assessing the risk of vitamin D deficiency in young women called ViDDPreS (Vitamin D Deficiency Predicting Scoring).

Researchers employed analysis tools and machine learning algorithms to identify two genes linked to rheumatoid arthritis and osteoporosis that could serve as diagnostic tools and potential targets for treatments. Drawing from a large database of genetic information, they gathered dozens of sequenced genomes from people with rheumatoid arthritis and osteoporosis to look for any similarities, using recently developed computational methods to narrow down their search. They identified genes ATXN2L and MMP14 as significantly associated with the progression of both rheumatoid arthritis and osteoporosis.

Researchers have used artificial intelligence tools to accelerate the understanding of the risk of specific cardiac arrhythmias when various parts of the heart are exposed to different thresholds of radiation as part of a treatment plan for lung cancer.

A high-sugar diet is seen as a risk factor for obesity and chronic illness. Researchers have analyzed data on sugar intake among children and adolescents in a long-term study, finding that intake has been declining steadily since 2010 -- but is still above the level recommended by the World Health Organization (WHO).

The health benefits of sunshine could outweigh the risks for people living in places with limited sunlight, such as parts of the UK, a study suggests. Exposure to higher levels of ultraviolet (UV) radiation in areas with low sunlight was linked to a drop in deaths from cardiovascular disease and cancer, according to the research.

Higher intake of heme iron, the type found in red meat and other animal products -- as opposed to non-heme iron, found mostly in plant-based foods -- was associated with a higher risk of developing type 2 diabetes (T2D) in a new study. While the link between heme iron and T2D has been reported previously, the study's findings more clearly establish and explain the link.

Researchers have developed a novel deep learning algorithm that outperformed existing computer-based osteoporosis risk prediction methods, potentially leading to earlier diagnoses and better outcomes for patients with osteoporosis risk.

Osteoporosis or the weakening of bones makes the aging population vulnerable to fractures and a decreased quality of life. The parathyroid hormone (PTH)-derived peptide -- teriparatide has demonstrated strong bone promoting effects. However, it is also to known to exert bone-resorbing effects. A new study uncovers a novel PTH-inducible target gene -- Gprc5a which suppresses the proliferation and differentiation of 'osteoblasts' or bone-forming cells, and may serve as a therapeutic target in the treatment of osteoporosis.

Healthy adults under the age of 75 are unlikely to benefit from taking more than the daily intake of vitamin D recommended by the Institutes of Medicine (IOM) and do not require testing for vitamin D levels. For children, pregnant people, adults older than 75 years and adults with high-risk prediabetes, the guideline recommends vitamin D higher than the IOM recommended daily allowance.

Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.

Obesity and metabolic disorders are increasingly significant global public health issues. In a novel study, a team of dermatologists evaluated the effect of ultraviolet (UV) exposure on appetite and weight regulation. They found that UV exposure raises norepinephrine levels, decreases leptin levels, and induces the browning of subcutaneous fat, thereby increasing energy expenditure. These results potentially pave the way for new approaches to prevent and treat obesity and metabolic disorders.

A new study sheds light on the complexities of achieving optimal vitamin D status across diverse populations. Despite substantial research on the determinants of vitamin D, levels of vitamin D deficiency remain high. Researchers believe their findings have significant implications for the development of tailored recommendations for vitamin D supplementation.

Researchers have found that vitamin D encourages the growth of a type of gut bacteria in mice which improves immunity to cancer.

The size of an individual snack piece not only influences how fast a person eats it, but also how much of it they eat, according to a new study. With nearly a quarter of daily calorie intake in the United States coming from snacks, these findings may have implications for helping people better understand how eating behavior impacts calorie and sodium intake.

Young to middle-aged women who reported drinking eight or more alcoholic beverages per week--more than one per day, on average--were significantly more likely to develop coronary heart disease compared with those who drank less, finds a study presented at the American College of Cardiology's Annual Scientific Session. The risk was highest among both men and women who reported heavy episodic drinking, or 'binge' drinking, and the link between alcohol and heart disease appears to be especially strong among women, according to the findings.

Air pollution and night-time outdoor light each were associated with harmful effects on brain health, finds new study.

The new diagnostic methodology, which will enable anticipating and preventing a greater number of cases of femur fracture, is the result of research conducted under a public-private alliance.

Shining a specific frequency of red light on a person's back for 15 minutes can significantly reduce blood sugar levels, according to a new study.

Rickets ran rife in children following the Industrial Revolution, but new research has found factory work and polluted cities aren't entirely to blame for the period's vitamin D deficiencies.

Having a high dietary intake of fish and vegetables at 1 year of age, and a low intake of sugar beverages, seems to protect against inflammatory bowel disease. These are the findings of a study with more than 80,000 children.

Researchers have developed a light-activatable prodrug nanomedicine for age-related macular degeneration (AMD) therapy. Through the intravenous injection of the nanomedicine and application of light irradiation to diseased eyes, anti-angiogenic and photodynamic combination therapy can be activated, offering a minimally invasive alternative for the treatment of AMD and other ocular disorders characterized by abnormal blood vessel growth.

A major clinical trial has found that vitamin D supplements do not increase bone strength or prevent bone fractures in children with vitamin D deficiency. The findings challenge widely held perceptions relating to the effects of vitamin D on bone health.

In diseased hearts, low-dose radiation therapy appears to improve heart function.

A review of 15 years' worth of data found that vitamin D supplementation during pregnancy was linked to reduced rates of asthma and wheezing in children compared to standard prenatal multivitamin.

Researchers have discovered that breast cancer cells expressing a cancer-driving gene heavily rely on vitamin B5 to grow and survive.

A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug's power against fungal infections while doing away with its toxicity, researchers report.

There are many creatures on our planet with more advanced senses than humans. Turtles can sense Earth's magnetic field. Mantis shrimp can detect polarized light. Elephants can hear much lower frequencies than humans can. Butterflies can perceive a broader range of colors, including ultraviolet (UV) light.

In a new study, scientists show that their synthetic melanin, mimicking the natural melanin in human skin, can be applied topically to injured skin, where it accelerates wound healing. These effects occur both in the skin itself and systemically in the body.

Imaging technology shows that bone-resorbing osteoclasts gather in distinct pockets, leading to new insights for osteoporosis and cancer treatment.

Artificial intelligence has exploded in popularity and is being harnessed by some scientists to predict which molecules could treat illnesses, or to quickly screen existing medicines for new applications. Researchers have used one such deep learning algorithm, and found that dihydroartemisinin (DHA), an antimalarial drug and derivative of a traditional Chinese medicine, could treat osteoporosis as well. The team showed that in mice, DHA effectively reversed osteoporosis-related bone loss.

Researchers have developed a human in vitro model that closely mimics the complexities of radiation-induced lung injury (RILI) and radiation dose sensitivity of the human lung. Using a previously developed microfluidic human Lung Alveolus Chip lined by human lung alveolar epithelial cells interfaced with lung capillary cells to recreate the alveolar-capillary interface in vitro, the researchers recapitulated many of the hallmarks of RILI, including radiation-induced DNA damage in lung tissue, cell-specific changes in gene expression, inflammation, and injury to both the lung epithelial cells and blood vessel-lining endothelial cells. By also evaluating the potential of two drugs to suppress the effects of acute RILI, the researchers demonstrated their model's capabilities as an advanced, human-relevant, preclinical, drug discovery platform.

Researchers have found that women who smoke during pregnancy are 2.6 times more likely to give birth prematurely compared to non-smokers -- more than double the previous estimate. The study also found that smoking meant that the baby was four times more likely to be small for its gestational age, putting it at risk of potentially serious complications including breathing difficulties and infections.

Thousands of people could be spared from a hip fracture each year if a new method to identify the risk of osteoporotic fractures were to be introduced in healthcare. This is the view of the researchers who are behind a new 3D-simulation method.

A new study suggests that extreme dietary habits involving carbohydrates and fats affect life expectancy. Researchers found that a low carbohydrate intake in men and a high carbohydrate intake in women are associated with a higher risk of all-cause and cancer-related mortality and that women with higher fat intake may have a lower risk of all-cause mortality. Their findings suggest that people should pursue a balanced diet rather than heavily restricting their carbohydrate or fat intake.

As life expectancy increases worldwide, age-associated diseases such as osteoporosis are having an increasing impact. Although early detection could help physicians intervene as soon as possible -- when treatment might offer the greatest benefit -- this type of detection is not yet possible with current osteoporosis diagnostic tests. Now, researchers have developed a biosensor that could someday help identify those most at risk for osteoporosis using less than a drop of blood.

Taking higher-than-recommended doses of vitamin D for five years reduced the risk of atrial fibrillation in older men and women, according to a new study.

Scientists have pinpointed a key driver of low bone density, a discovery that may lead to improved treatments with fewer side effects for women with osteoporosis. The findings reveal that loss of an epigenetic modulator, KDM5C, preserves bone mass in mice. KDM5C works by altering epigenetic 'marks,' which are akin to 'on' and 'off' switches that ensure the instructions written in DNA are used at the right time and in the right place.

The fruit of the cocklebur plant, which grows worldwide and is often considered a noxious weed, has antioxidant and anti-inflammatory components that could make it useful as a skin protectant, according to new research.

A research team has discovered a novel mechanism to process DNA damage induced by a next-generation cancer therapy (heavy ion therapy).

Pregnant women should dim the lights in their home and turn off or at least dim their screens (computer monitors and smartphones) a few hours before bedtime to reduce the risk of gestational diabetes mellitus, a new study shows. Women who developed gestational diabetes in the multisite study had greater light exposure in the three hours before sleep onset. They did not differ in their light exposure during daytime or sleep or in their activity levels compared to those who did not develop it.

Elevated levels of air pollutants are associated with bone damage among postmenopausal women, according to new research. The effects were most evident on the lumbar spine, with nitrous oxides twice as damaging to the area than seen with normal aging.

Researchers have found new evidence that vitamin D may be metabolized differently in people with an elevated body mass index (BMI). The study is a new analysis of data from the VITAL trial, a large nationwide clinical trial that investigated whether taking vitamin D or marine omega-3 supplements could reduce the risk of developing cancer, heart disease, or stroke.

Reformulating packaged foods available in Australia to contain less sodium may save about 1,700 lives per year, according to a new study. Using the World Health Organization's (WHO) recommendations for reducing the population's sodium intake, the researchers estimate following the WHO sodium guidance may also prevent nearly 7,000 annual diagnoses of heart disease, kidney disease and stomach cancer in Australia.

A new way of thinking about Alzheimer's disease has yielded a discovery that could be the key to stopping the cognitive decline seen in Alzheimer's and other neurodegenerative diseases, including ALS and Parkinson's.

The drugs, called NRTIs, have the potential to prevent a million cases of Alzheimer's every year, the researchers believe.

A vitamin supplement that improves metabolism in the eye appears to slow down damage to the optic nerve in glaucoma. The researchers behind the study have now started a clinical trial on patients.

A new study examines the choices healthy research volunteers make when given the opportunity to learn their risk of developing Alzheimer's disease dementia. The researchers found a large discrepancy between the percentage of participants who said they would like to learn their risk if such estimates became available and the percentage who followed through to learn those results when given the actual opportunity.

Researchers have shown they can inexpensively nanomanufacture silk microneedles to precisely fortify crops, monitor plant health, and detect soil toxins.

A new study found that a gene recently recognized as a biomarker for Alzheimer's disease is actually a cause of it, due to its previously unknown secondary function that triggers a pathway that disrupts how cells in the brain turn genes on and off.

Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia symptoms. This is evident in the levels of the protein 'beta-synuclein'.

Differences in the distribution of certain proteins and markers in the brain may explain why some people first experience vision changes instead of memory loss in Alzheimer's disease, finds a new study.

Elite athletes have shared their worries about their sports career after pregnancy.

A newly developed blood test for Alzheimer's disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a new study.

An experimental drug appears to reduce the risk of Alzheimer's-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a new study. The findings suggest -- for the first time in a clinical trial -- that early treatment to remove amyloid plaques from the brain many years before symptoms arise can delay the onset of Alzheimer's dementia.

Researchers have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a second.

Women with blood pressure levels in a range considered clinically normal during pregnancy but no mid-pregnancy drop in blood pressure face an increased risk of developing hypertension in the five years after giving birth. These women -- about 12% of the population studied -- would not be flagged as high-risk by current medical guidelines, but the new findings could help identify them as candidates for early intervention.

Higher levels of the minerals copper and manganese in pregnant women were associated with lower blood pressure and a reduced risk of developing high blood pressure decades later, according to a long-term study.

A new study suggests a promising alternative to previous attempts to remove the sticky, toxic amyloid beta plaques from brains with Alzheimer's Disease: enhancing the brain's own immune cells to clear these plaques more effectively. The findings could reshape the future of Alzheimer's treatments, shifting the focus from simply removing plaques to harnessing the brain's natural defenses.

Air pollution contributes to nearly 7 million premature deaths each year, and its effects go far beyond the lungs. Breathing in wildfire smoke or automobile-related city smog doesn't just increase the risk of asthma and heart disease -- it may also contribute to brain conditions as diverse as Alzheimer's and autism. Scientists have discovered how a chemical change in the brain -- which can be triggered by inflammation and aging as well as toxins found in air pollution, pesticides, wildfire smoke and processed meats -- disrupts normal brain cell function. Known as S-nitrosylation, this chemical change prevents brain cells from making new connections and ultimately results in cellular death, the team discovered.

Identifying and treating risk factors for depression, anxiety and other psychological health conditions during pregnancy and postpartum may improve short- and long-term health outcomes for both mother and child, according to a new scientific statement.

Meeting the minimum requirement for vitamin B12, needed to make DNA, red blood cells and nerve tissue, may not actually be enough -- particularly if you are older. It may even put you at risk for cognitive impairment.

Maternal vitamin D levels in the first trimester were related to both prenatal growth and pregnancy outcomes, according to a new study. Low vitamin D levels during the first trimester of pregnancy were associated with higher rates of preterm birth and decreased fetal length.

By analyzing almost 10,000 pregnancies, researchers discovered previously unidentified combinations of risk factors linked to serious negative pregnancy outcomes, finding that there may be up to a tenfold difference in risk for infants who are currently treated identically under clinical guidelines.

Researchers publish landmark analysis on the impacts of prenatal vitamins on mothers and newborns.

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem cells, and neural activation processes.

The B vitamin mitigates manganese neurotoxicity, which produces symptoms that resemble Parkinson's disease. The vitamin improves dopamine production in the brain and offers potential therapeutic benefits.

Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research points to a novel -- and noble -- approach: using Xenon gas. The study found that Xenon gas inhalation suppressed neuroinflammation, reduced brain atrophy, and increased protective neuronal states in mouse models of Alzheimer's disease. A phase 1 clinical trial of the treatment in healthy volunteers will begin in early 2025.

Declining blood levels of two molecules that occur naturally in the body track closely with worsening Alzheimer's disease, particularly in women. Levels were found to drop gradually, from women with no signs of memory, disorientation, and slowed thinking to those with early signs of mild cognitive impairment. Decreases were more prominent in women with moderate or severe stages of the disease. Declines in men were evident in only one molecule, revealing a disease-specific difference between the men and women.

Researchers have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer's disease in a subset of people. It is believed most humans are exposed to this virus -- called cytomegalovirus or HCMV -- during the first few decades of life. According to the new research, in some people, the virus may linger in an active state in the gut, where it may travel to the brain via the vagus nerve -- a critical information highway that connects the gut and brain. Once there, the virus can change the immune system and contribute to other changes associated with Alzheimer's disease. This virus may be a target for antiviral treatments.

Many vitamins are produced in chemical factories, often synthetically, but researchers have succeeded in developing a natural and simple method for producing vitamin B2: by gently heating lactic acid bacteria. This could be a game-changer in developing countries, where many suffer from vitamin B2 deficiency, enabling fortification with B2 directly in local kitchens.

Researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study also integrates drug databases with real-world patient data to identify FDA-approved drugs that may be repurposed to target disease-associated microglia in Alzheimer's disease without affecting the healthy type.

New research has found that women who have had both ovaries surgically removed before the age of 50 and carry a variant of the apolipoprotein gene, the APOE4 allele, are at high risk of late-life Alzheimer disease (AD). Use of hormone therapy mitigates this risk.

Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a new study. The researchers emphasized that lifestyle modifications targeted at reducing this fat could influence the development of Alzheimer's disease.

Children of mothers who took certain anti-seizure medications while pregnant do not have worse neurodevelopmental outcomes at age 6, according to a long-running study.

New research reveals many prenatal vitamins don't contain enough of the nutrients that are essential for a healthy pregnancy, while others contain harmful levels of toxic metals. The study checked the amounts of choline and iodine in nonprescription and prescription prenatal vitamins. The research also checked for toxic metals like arsenic, lead and cadmium. The researchers tested a sample of 47 different prenatal vitamins (32 nonprescription and 15 prescription products) bought from online and local stores where people commonly shop. They then measured the actual amounts of choline and iodine in their lab versus what was on the label and also checked for arsenic, lead and cadmium. They compared their findings with official safety standards within 20% of the claimed amount.

A new study found that, among nearly 775,000 pregnant people in Massachusetts, 31 percent of these individuals had at least one unscheduled emergency visit to the hospital, and 3.3 percent had four or more unscheduled hospital visits. The latter group was nearly 50 percent more likely to experience severe maternal morbidity (SMM), which encompasses a range of complications during labor or childbirth that can lead to poor maternal outcomes such as aneurysms, eclampsia, kidney and heart failure, and sepsis.

Clinics and hospitals currently defer medication abortion until ultrasound confirms a pregnancy inside the uterus. However, a large international study now indicates that treatment can be equally effective and safe even before the sixth week of pregnancy.

Children whose mothers took extra vitamin D during pregnancy continue to have stronger bones at age seven, according to research.

By examining RNA in hundreds of thousands of individual brain cells, scientists further support that alcohol use disorder could accelerate Alzheimer's disease progression, paving the way for future targeted treatments.

Researchers published a study examining symptoms, health outcomes, and physical function over time in older adults with and without Alzheimer's disease and related dementias and polypharmacy.

In a study, researchers use neuroimaging methods to examine brain resilience in regions of the brain linked to language and aging. They found that the hippocampus in bilinguals with Alzheimer's disease was noticeably larger than those who were monolingual when matched for age, education, cognitive function and memory, which suggests that there may be some form of brain maintenance related to bilingualism.

A new study has found that folate may weaken the link between blood-lead levels in pregnant women and autistic-like behaviors in their children.

Alzheimer's disease may damage the brain in two distinct phases, based on new research using sophisticated brain mapping tools. According to researchers who discovered this new view, the first, early phase happens slowly and silently -- before people experience memory problems -- harming just a few vulnerable cell types. In contrast, the second, late phase causes damage that is more widely destructive and coincides with the appearance of symptoms and the rapid accumulation of plaques, tangles, and other Alzheimer's hallmarks.

The protein 'MIPS' changes its internal structure when it becomes active. Its disordered active centre becomes a defined structure with special functions. The protein plays a key role in the production of inositol, which is also known as vitamin B8, and fulfills important tasks in the body. Researchers have succeeded for the first time in observing the protein as it re-structures.

Two new papers by a team of researchers demonstrate that evaluating microRNAs in blood can be used not only to diagnose mild cognitive impairment (MCI) but also, critically, to predict the conversion from MCI to dementia due to Alzheimer's disease. Moreover, the researchers uncovered microRNA candidate molecular biomarkers that associate with current Amyloid, Tau, and Neurodegeneration (A/T/N) Alzheimer's biomarkers.

Researchers follow the dramatic changes that occur in the brain throughout the course of pregnancy.

With ketamine for depression & PTSD growing rapidly in use, but with concerns about potential impact on a fetus, a study shows wide variation in pregnancy testing & contraception guidance at clinics offering IV and nasal spray treatment.

More than half of the global population consumes inadequate levels of several micronutrients essential to health, including calcium, iron, and vitamins C and E, according to a new study. It is the first study to provide global estimates of inadequate consumption of 15 micronutrients critical to human health.

A collaborative investigation among experts in Alzheimer's disease and multiple sclerosis (MS) finds evidence that MS patients are less likely to have amyloid plaques, a hallmark of Alzheimer's disease, than adults without MS.

A new study has identified why a diet rich in magnesium is so important for our health, reducing the risk of DNA damage and chronic degenerative disorders.

Living less than about one-third of a mile from pesticide use prior to conception and during early pregnancy could increase the risk of stillbirths.

A study of horses -- which share many important similarities with humans in their chromosomes and pregnancies -- revealed that 42% of miscarriages and spontaneous abortions in the first two months of pregnancy were due to complications from an extra set of chromosomes, a condition called triploidy.

A new tool to track the neurons and molecules activated in the brain by psychedlic drugs could help scientists unlock the benefits of psychedelic treatments for patients with brain disorders.

Scientists found that decreasing folate intake can support healthier metabolisms in aging animal models, challenging the conventional belief that high folate consumption universally benefits health.

Researchers have developed a way to study aged neurons in the lab without a brain biopsy, allowing them to accurately model the effects of aging in the development of late-onset Alzheimer's disease. By studying these cells, the researchers identified aspects of cells' genomes -- called retrotransposable elements, which change their activity as we age -- in the development of late-onset Alzheimer's disease. The findings suggest new treatment strategies targeting these factors.

Researchers are working to create the first strain of mice that's genetically susceptible to late-onset Alzheimer's, with potentially transformative implications for dementia research.

Genomics and lab studies reveal numerous findings, including a key role for Reelin amid neuronal vulnerability, and for choline and antioxidants in sustaining cognition.

A world-first study has found low-dose aspirin may treat flu-induced blood vessel inflammation, creating better blood flow to the placenta during pregnancy.

The blood-brain barrier -- a network of blood vessels and tissues that nurtures and protects the brain from harmful substances circulating in the blood -- is disrupted in Alzheimer's disease. Now, researchers have uncovered unique molecular signatures of blood-brain barrier dysfunction that could point to new ways to diagnose and treat the disease.

A study has revealed a link between gut microbiota and Parkinson's disease. The researchers discovered a decrease in bacterial genes related to the synthesis of vitamins B2 and B7. The lack of these genes was associated with reduced intestinal short-chain fatty acids and polyamines, agents that maintain the intestinal barrier and prevent the leakage of toxins into the blood that can then access the brain. Using B vitamin therapy to address these deficiencies may restore the barrier and treat Parkinson's disease.

The number of individuals in the U.S. who had chronic hypertension or chronic high blood pressure during pregnancy doubled between 2008 and 2021.

At least 5.8 million Americans are currently living with Alzheimer's disease, which is the most common form of dementia. There is no cure for Alzheimer's, in part because scientists do not yet have a full understanding of what causes the disease. But a new study is shedding light on the molecular drivers that could contribute to Alzheimer's progression.

Late last year, geneticists made the discovery that morning sickness's most serious presentation, hyperemesis gravidarum (HG), is caused by the hormone GDF15, not human chorionic gonadotropin as previously thought. Researchers dispel common morning sickness myths and discusses potential treatments, including sensitizing people to GDF15 prior to pregnancy, similar to the way we treat allergies.

Scientists in Japan have discovered that a natural compound found in a type of ginger called kencur can throw cancer cells into disarray by disrupting how they generate energy. While healthy cells use oxygen to make energy efficiently, cancer cells often rely on a backup method. This ginger-derived molecule doesn t attack that method directly it shuts down the cells' fat-making machinery instead, which surprisingly causes the cells to ramp up their backup system even more. The finding opens new doors in the fight against cancer, showing how natural substances might help target cancer s hidden energy tricks.

Scientists have developed new tools to improve gene therapy in advanced stages of inherited retinal diseases (IRDs) such as retinitis pigmentosa and Leber congenital amaurosis.

A team of researchers has identified a promising new approach that may one day help to restore vision in people affected by macular degeneration and other retinal disorders.

Researchers have successfully developed a novel drug to restore vision. The treatment method restores vision through retinal nerve regeneration.

Researchers have developed eye drops that extend vision in animal models of a group of inherited diseases that lead to progressive vision loss in humans, known as retinitis pigmentosa.

Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal developmental pathway to trigger cancer cell death.

A team of scientists has identified that an eye condition affecting the retina, the light-sensing tissue in the back of the eye, may serve as an early indicator for Alzheimer's disease.

Researchers have conducted one of the largest eye studies in the world to reveal new insights into retinal thickness, highlighting its potential in the early detection of diseases like type 2 diabetes, dementia and multiple sclerosis.

Maternal vitamin D levels in the first trimester were related to both prenatal growth and pregnancy outcomes, according to a new study. Low vitamin D levels during the first trimester of pregnancy were associated with higher rates of preterm birth and decreased fetal length.

Researchers have identified new drug targets for therapies that could benefit patients with different forms of retinitis pigmentosa and other inherited retinal diseases. Using advanced proteomics techniques, they unveiled shared critical pathways in retinitis pigmentosa disease models. The study represents significant progress in understanding how the proteome may change in different retinal dystrophies.

Human stem cell transplants successfully repaired macular holes in a monkey model, researchers report. After transplantation, the macular holes were closed by continuous filling of the space with retinal tissue.

Over half of people with iron deficiency were found to still have low iron levels three years after diagnosis, and among patients whose condition was effectively treated within that timeframe, they faced longer-than-expected delays, pointing to substantial gaps in appropriate recognition and efficient treatment of the condition, according to a new study.

In what they believe is a solution to a 30-year biological mystery, neuroscientists say they have used genetically engineered mice to address how one mutation in the gene for the light-sensing protein rhodopsin results in congenital stationary night blindness.

Researchers have discovered the virus that causes COVID-19 can breach the protective blood-retinal-barrier with potential long-term consequences in the eye.

Scientists have created a biocompatible artificial vitreous body derived from algae-derived carbohydrates.

Retinoic acid, the active state of Vitamin A, appears to regulate how stem cells enter and exit a transient state central to their role in wound repair.

Researchers have discovered profound similarities and surprising differences between humans and insects in the production of the critical light-absorbing molecule of the retina, 11-cis-retinal, also known as the 'visual chromophore.' The findings deepen understanding of how mutations in the RPE65 enzyme cause retinal diseases, especially Leber congenital amaurosis, a devastating childhood blinding disease.

Scientists discovered a new target for reversible, non-hormonal male birth control. The drug, an HDAC inhibitor, blocked sperm production and fertility in male mice without affecting libido or future reproduction.

Researchers identified a retinal disease to evaluate the success of gene and cell replacement therapy.

In a new study, researchers combined OCT retinal imaging, genetics and big data to estimate how likely a person is to develop eye and systemic diseases in the future. They found significant associations between the thinning of different retinal layers and increased risk of developing eye, neuropsychiatric, cardiac, metabolic, and pulmonary diseases and identified genes that are associated with retinal layer thickness. Their hope is one day patients can be provided more personalized risk assessments and referred to specialists for preventive and treatment plans for eye and other diseases.

With human retinas grown in a petri dish, researchers discovered how an offshoot of vitamin A generates the specialized cells that enable people to see millions of colors, an ability that dogs, cats, and other mammals do not possess. The findings increase understanding of color blindness, age-related vision loss, and other diseases linked to photoreceptor cells. They also demonstrate how genes instruct the human retina to make specific color-sensing cells, a process scientists thought was controlled by thyroid hormones.

In a comparative analysis across vertebrates of the many cell types in the retina -- mice alone have 130 types -- researchers concluded that most cell types have an ancient evolutionary history. Their remarkable conservation across species suggests that the retina of the last common ancestor of all mammals, which roamed the earth some 200 million year ago, must have had a complexity rivaling the retina of modern mammals.

According to new research, T cells have a nuclear receptor doing something very odd—but very important—to help them fight pathogens and destroy cancer cells. This receptor, called retinoic acid receptor alpha, is known to control gene expression programs in the nucleus, but it also now appears to operate outside the cell nucleus to coordinate the early events triggered at the cell surface that lead to T cell activation.

For more than 50 years, it has been suspected that fat cells constantly remodel the lipids they store. Researchers have now demonstrated this process directly for the first time using culture cells. Among other things, the study shows that the cells quickly eliminate harmful fatty acids. They refine others into molecules that can be used more effectively. In the long term, this turns the components of palm fat into the building blocks of high-quality olive oil, for example.

For the first time, researchers have developed a form of the omega-3 fatty acid docosahexaenoic acid (DHA) that is capable of crossing into the eye's retina to ward off visual declines related to Alzheimer's disease, diabetes and other disorders.

Metabolic pathways consist of a series of biochemical reactions in cells that convert a starting component into other products. There is growing evidence that metabolic pathways coupled with external stress factors influence the health of cells and tissues. Many human diseases, including retinal or neurodegenerative diseases, are associated with imbalances in metabolic pathways.

Researchers use UK Biobank data to uncover new information about rare diseases of the eye.

Researchers have found new evidence that vitamin D may be metabolized differently in people with an elevated body mass index (BMI). The study is a new analysis of data from the VITAL trial, a large nationwide clinical trial that investigated whether taking vitamin D or marine omega-3 supplements could reduce the risk of developing cancer, heart disease, or stroke.

Researchers have found that a defect in an enzyme called APT1 interferes with the ability to secrete insulin, contributing to the development of Type 2 diabetes in people who are overweight or obese.

Researchers have developed a new way to fortify foods with vitamin A, which they hope could help to improve the health of millions of people around the world. In a new study, they showed that encapsulating vitamin A in a protective polymer prevents the nutrient from being broken down during cooking or storage.

A new study has identified that heart attack, stroke and heart failure are linked to a specific type of age-related macular degeneration.

New research gives strong evidence that vitamin D deficiency is associated with premature death, prompting calls for people to follow healthy vitamin D level guidelines.

Researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell's nucleus. The resulting comprehensive gene regulatory network provides insights into regulation of gene expression in general, and in retinal function, in both rare and common eye diseases.

Researchers have developed a simple and fast way to perform optoretinography, an imaging technique that measures light-induced functional activity in the eye's retina, the network of neurons in the back of our eyes responsible for detecting light and initiating vision. More than 50 percent of people in the U.S. over age 60 are affected by diseases that impact the retina's function in ways that reduce eyesight and can progress to blindness if not treated. The new approach could help accelerate the development of new treatments for eye diseases.

Researchers have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early childhood.

Researchers have demonstrated that the APOE4 gene variant, which increases risk for Alzheimer's but decreases risk of glaucoma, blocks a disease cascade that leads to the destruction of retinal ganglion cells in glaucoma. Additionally, they showed in mouse models that the death of retinal ganglion cells can be prevented by using medications to inhibit a molecule called Galectin-3, which is regulated by the APOE gene. These findings taken together emphasize the critical role of APOE in glaucoma and suggest that Galectin-3 inhibitors hold promise as a glaucoma treatment.

Scientists have challenged the widespread belief that shift workers adjust to the night shift, using data drawn from wearable tech.

Scientists have developed a new, experimental human cell line from retinal pigment epithelial cells. Called ABC, these cells so closely resemble and retain the properties of native retinal pigment epithelial (RPE) cells, the research team has shown that they are a reliable cell system to study retinal degenerative diseases.

Scientists have developed a bio-functional thermogel, a type of synthetic polymer, to prevent retinal scarring caused by failed retinal detachment repair surgery. Proliferative vitreoretinopathy (PVR) occurs when the retinal scarring prevents the retina from healing and falling back into place, and accounts for more than 75 per cent of failed retinal detachment surgeries, and may result in vision loss or blindness if left unrepaired.

A new, detailed genetic roadmap of glaucoma will help researchers develop new drugs to combat the disease, by identifying potential target areas to stall or reverse vision loss.

The AREDS2 dietary supplement formula not only reduces risk of lung cancer due to beta-carotene, but is also more effective at reducing risk of AMD progression, compared to the original AREDS formula.

Researchers have identified distinct differences among the cells comprising a tissue in the retina that is vital to human visual perception. The scientists discovered five subpopulations of retinal pigment epithelium (RPE) -- a layer of tissue that nourishes and supports the retina's light-sensing photoreceptors. Using artificial intelligence, the researchers analyzed images of RPE at single-cell resolution to create a reference map that locates each subpopulation within the eye.

New research shows that a treatment for retinal vein occlusion yields long-lasting vision gains, with visual acuity remaining significantly above baseline at five years. However, many patients require ongoing treatment.

A new study indicates base editing may provide long-lasting retinal protection and prevent vision deterioration in patients with inherited retinal degeneration, specifically in Leber congenital amaurosis (LCA) patients.

Researchers have identified a gene necessary for the survival of retinal ganglion cells -- a class of neurons located in the retina that are critical for vision.

Animal and cell studies show that as retinal cells die in degenerative eye diseases, they make other cells hyperactive, creating noise that further obscures vision. Tests to prove this in humans are hard to conduct, however. Antabuse, an approved drug used to wean people off alcohol, should tamp down this hyperactivity and conclusively show whether hyperactivity plays a role in humans, potentially driving work to find better drugs to help those with progressive vision loss.

A research group has revealed that amyloid-beta detected in blood is secreted from peripheral tissues (pancreas, adipose tissue, skeletal muscle, liver, etc.) that are sensitive to glucose and insulin.

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

A trial found that taking a much higher dose of vitamin D than recommended for five years did not affect total mortality or the incidence of cardiovascular disease or cancer in older men and women.

A study has discovered how late-onset retinal degeneration can develop and a surprising potential therapeutic -- metformin.

Free from the sun, vitamin D delivers a natural source for one of the hormones essential to our bodies, especially the bones. But when you're down on this essential nutrient, it's not only your bones that could suffer, but also your cardio health, according to new research.

A recent study examining the therapeutic potential of photoreceptor precursors, derived from clinically compliant induced pluripotent stem cells (iPSC), has demonstrated the safety and therapeutic potential of clinically compliant iPSC-derived photoreceptor precursors as a cell replacement source for future clinical trials.

Approximately 10% of new coronary heart disease cases occurring within a decade of middle age could be avoided by preventing iron deficiency, suggests a new study.

Using data from over 283,600 people in UK Biobank, researchers have found that people who work night shifts are at increased risk of developing an irregular and often abnormally fast heart rhythm called atrial fibrillation, and they are also at an increased risk of heart disease. Women and people who don't exercise regularly are most at risk.

Researchers have identified new biomarkers that may advance the early detection of diabetic retinopathy, the most common diabetic eye disease and a leading cause of blindness in U.S. adults.

New research has found that people who eat a diet rich in vitamin K have up to a 34 percent lower risk of atherosclerosis-related cardiovascular disease (conditions affecting the heart or blood vessels).

A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to new research. The findings suggest a way forward for developing neuroprotective therapies for glaucoma, a leading cause of visual impairment and blindness.

Researchers have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye. The peptides might someday be used to treat degenerative retinal diseases, such as age-related macular degeneration (AMD).

Lab animals deficient in vitamin D crave and become dependent on opioids, which is curbed when normal levels of the vitamin are restored. Human health records indicate that people with low vitamin D are more likely to use and misuse opioids. Study results suggest a potential role for vitamin D supplementation in fighting opioid addiction.

In a retrospective study of individuals tested for COVID-19, vitamin D levels above those traditionally considered sufficient were associated with a lower risk of COVID-19.

Tufts University scientists are aiming to revolutionize the future of weight loss drugs by engineering a new compound that targets four gut hormones instead of the usual one to three. These next-gen tetra-functional peptides may overcome the limitations of current drugs like Ozempic and Mounjaro especially their nausea, muscle loss, and rebound weight gain.

A team of scientists has identified specialized neurons in the brain that store "meal memories" detailed recollections of when and what we eat. These engrams, found in the ventral hippocampus, help regulate eating behavior by communicating with hunger-related areas of the brain. When these memory traces are impaired due to distraction, brain injury, or memory disorders individuals are more likely to overeat because they can't recall recent meals. The research not only uncovers a critical neural mechanism but also suggests new strategies for treating obesity by enhancing memory around food consumption.

New research reveals a surprising downside to calorie-cutting diets: a link to higher levels of depressive symptoms, especially in men and those who are overweight. Despite popular beliefs that healthy eating boosts mental wellness, real-life restrictive diets may be nutritionally unbalanced, potentially harming emotional and cognitive health.

An analysis of data from a national health survey conducted before the pandemic found that pizza, soup and chicken are some of the main sources of sodium (salt) intake for people in all racial and ethnic groups. The study also showed clear differences among adults based on race and ethnicity.

Researchers find high-fat diets set off metabolic dysfunction in cells, leading to weight gain, but these effects can be reversed by treatment with an antioxidant.

Throwing a little heat on your meal might be an effective strategy for cutting back on calories, according to a new study.

Small clinical study with obese dieters who had chronic health problems found that eating balanced meals and including craved foods with those meals helped dieters manage cravings, even into the yearlong maintenance phase of the program.

Researchers have discovered a new way to reduce obesity. Supplying the gut with extra acetate reduces fat and liver mass in both normal and obese mice, as long as bacteria of the Bacteroides species is also present. When both these conditions are met, gut bacteria can eliminate more sugars from the gut and promote the burning of fats for energy in the host.

Intakes of dietary fiber and high-quality carbohydrates in midlife are linked to increased likelihood of healthy aging and other positive health outcomes in older women. Higher intakes of refined carbohydrates and starchy vegetables were associated with lower odds of healthy aging.

Having school dinners rather than packed lunches could encourage picky eating 13-year-olds to eat a wider variety of foods, according to a new study.

Consumption of ultra-processed foods, such as sugar-sweetened beverages, potato chips and packaged cookies, may be associated with adverse health outcomes. Study finds each additional 100 grams/day consumption of ultra-processed foods increased risk of hypertension, cardiovascular events, cancer and more.

A landmark study exploring consumption of chips, frozen pizzas, breakfast cereals and other ultra-processed foods typically loaded with fat, sugar and additives has confirmed these foods are directly and significantly linked to poor health outcomes.

For almost 60 years, measuring cholesterol levels in the blood has been the best way to identify individuals at high risk of cardiovascular disease. In a new study, researchers have shown comprehensively that a combination of two lipoprotein markers, measured in a simple blood test, can give more accurate information about individual risk of heart disease than the current blood cholesterol test, potentially saving lives.

Persistently high blood sugar and insulin resistance significantly increased the risk of worsening functional and structural heart damage during growth from adolescence to young adulthood, a new study shows.

A new study asked three questions about muscle protein synthesis in response to a nine-day diet and weight training regimen: First, does the source of protein -- plant or animal-based -- make any difference to muscle gain? Second, does it matter if total daily protein intake is evenly distributed throughout the day? And third, does a moderate but sufficient daily protein intake influence any of these variables? The answer to all three questions is 'no,' the researchers found.

The intermittent fasting diet, which involves periods of severe calorie restriction, may be on the way out, as research is suggesting that rather than drastically reducing calories, people can achieve similar metabolic benefits by cutting back on carbs.

Research shows that the biological parents' genes affect the child's insulin function and capacity to regulate blood sugar levels and blood lipids in different ways. Such knowledge may be used to to develop preventive treatments that reduce the child's risk of developing type 2 diabetes and cardiovascular disease.

The increasing number of people with eating disorders and a lack of national guidance for support teams has led to researchers calling for a new national strategy that includes specific guidance to support the remote delivery of eating disorder services.

A new study indicates that when healthy adults pair an eight-hour eating window with regular exercise, they lose more fat -- without sacrificing lean muscle -- compared to exercise alone.

Glucose is life's main energy source. But a new study reveals a surprising role as a master manipulator of tissue maturation, hinting at its importance in diabetes and cancer.

Many youth have heart disease risk factors by their late teens, and preventing or addressing these risks early may reduce the risk of developing cardiovascular disease in the future, according to a new scientific statement.

Many obese people report losing pleasure in eating rich foods -- something also seen in obese mice. Scientists have now discovered the reason. Long-term high-fat diets lower levels of neurotensin in the brain, disrupting the dopamine pleasure network and decreasing the desire to eat high-fat foods. Raising neurotensin levels in mice brings back the pleasure and aids weight loss. Bringing back the pleasure could help people break the habit of overeating.

An algorithm that learned from tens of thousands of nutrition prescriptions for premature babies could reduce medical errors and better identify what nutrients the smallest patients need.

Maintaining a healthy diet rich in plant-based foods, with low to moderate intake of healthy animal-based foods and lower intake of ultra-processed foods, was linked to a higher likelihood of healthy aging -- defined as reaching age 70 free of major chronic diseases and with cognitive, physical, and mental health maintained, according to a new study. The study is among the first to examine multiple dietary patterns in midlife in relation to overall healthy aging.

Up to 25% of new mothers suffer from postpartum depression, which can significantly impact their parenting behavior and the wellbeing of their children. A new study looks at long-term effects of early maternal depression on children, underscoring the need to provide adequate support for mothers who might be struggling.

A new study analyzing diet, average plasma sugar levels and cancer prevalence in some 273 vertebrate species showed surprising results. The study found no significant link between diet and plasma sugar levels across nonhuman vertebrate species, suggesting that glucose regulation is likely influenced more by evolutionary and physiological adaptations than diet alone. Birds in particular did not suffer increased cancer rates compared with mammals and reptiles, despite having higher blood glucose levels, which are associated with increased cancer risk in other animals, including humans.

Just a few days of eating a diet high in saturated fat could be enough to cause memory problems and related brain inflammation in older adults, a new study in rats suggests.

Gut microbes that were thought to feed exclusively on dietary fiber also get fed sugar from our guts, from which they produce short-chain fatty acids that are crucial to many body functions. The discovery of this symbiotic relationship also points the way to developing novel therapeutics.

New research reveals that a mother's diet during pregnancy -- characterized by a Western dietary pattern high in fat and sugar and low in fresh ingredients -- may increase the risk of neurodevelopmental conditions such as ADHD and autism in children. Researchers see potential for targeted dietary interventions during pregnancy to reduce this risk.

Researchers have shown how a low carbohydrate diet can worsen the DNA-damaging effects of some gut microbes to cause colorectal cancer. The study compared the effects of three different diets in combination with specific gut bacteria on colorectal cancer development in mice.

Researchers have discovered a new way in which the liver regulates its consumption of sugar and fat. This could potentially increase the effectiveness of weight-loss and diabetes medication.

Two new papers describe a significant advance in understanding the complex functions of the metabolic network.

Because almost no existing programs focus specifically on reducing ultra-processed food (UPF) intake, researchers recently designed an intervention that included a variety of tactics to target the uniquely problematic aspects of UPFs. On average, participants successfully reduced their UPF intake by almost half.

The causes of obesity are complex and influenced by many factors. While research has highlighted connections between sleep, eating patterns and weight gain, scientists remain uncertain of the role of the circadian system -- the biological clock -- in shaping eating patterns. But a new study reveals a distinct relationship between circadian rhythms, weight and eating habits in adolescents, a vulnerable age group whose eating patterns influence their lifelong health. The study found that adolescents whose weight was classified as 'overweight' or 'obese' consumed more calories later in the day compared to participants with healthy weights.

New research has found that putting lower-calorie meal choices at the top of a restaurant menu, and reducing the availability of high-calorie options, makes teenagers more likely to order the healthier options.

Depression affects 280 million people worldwide. The mental illness has been proven to lead to changes in eating behavior. Researchers have discovered that although patients with depression generally have less appetite, they prefer carbohydrate-rich foods.

Body weight and body mass index alone are not enough to predict whether someone will develop a metabolic disease. A new atlas of cells in fat tissue could help to explain why some overweight people stay healthy, while others do not.

It's a little pill with big responsibilities. But despite its primary role to prevent pregnancy, the contraceptive pill (or 'the Pill') could also help reduce the risk of ovarian cancer, according to new research.

It's well known that consuming sugary drinks increases the risk of diabetes, but the mechanism behind this relationship is unclear. Now researchers show that metabolites produced by gut microbes might play a role. In a long-term cohort of US Hispanic/Latino adults, the researchers identified differences in the gut microbiota and blood metabolites of individuals with a high intake of sugar-sweetened beverages. The altered metabolite profile seen in sugary beverage drinkers was associated with a higher risk of developing diabetes in the subsequent 10 years. Since some of these metabolites are produced by gut microbes, this suggests that the microbiome might mediate the association between sugary beverages and diabetes.

Calorie labels on restaurant menus are negatively impacting people with eating disorders, according to a new study. The review found that individuals who have been diagnosed with an eating disorder changed their behaviors if presented with a menu featuring calorie labels.

A study shows that patients with obesity and fatty liver-related cirrhosis who had bariatric (weight-loss) surgery significantly lowered their future risk of developing serious liver complications compared with patients who received medical therapy alone.

Many people struggle to maintain a healthy weight, and choosing the optimal meals for weight loss can be challenging. A research team has developed a weight management program that helps individuals plan meals with the assistance of a web application and support from a registered dietitian. In a new study, they discuss the app's features, development, and implementation.

A research team identified the brain's food-specific memory system and its direct role in overeating and diet-induced obesity. They found a specific population of neurons in the mouse brain that encode memories for sugar and fat, profoundly impacting food intake and body weight.

A research team reports on a novel observation of a plant protection mechanism in response to salt stress. The study opens new avenues of research to strengthen food security.

Scientists have conducted a pioneering study on the benefits of intermittent fasting. Not eating anything from 5 p.m. until 9 a.m. the following day (early fasting) helps to a greater extent to improve blood sugar regulation and reduce abdominal subcutaneous fat, i.e. the fat just under the skin.

New research finds a pervasive low-quality diet among pregnant and postpartum individuals, reflecting 'an urgent need for widespread improvement.'

Higher calorie foods were preferred among individuals with and without obesity despite similar taste and texture, according to a new study.

A new study of plant-based drinks reveals a common issue: they are lacking in proteins and essential amino acids compared to cow's milk. The explanation lies in their extensive processing, causing chemical reactions that degrade protein quality in the product and, in some cases, produce new substances of concern.

Researchers developed a non-invasive imaging technique that enables laser light to penetrate deeper into living tissue, capturing sharper images of cells. This could help clinical biologists study disease progression and develop new medicines.

A diet high in ultra-processed foods is associated with higher amounts of fat stored inside thigh muscles, regardless of the amount of calories consumed or level of physical activity, according to a new study. Higher amounts of intramuscular fat in the thigh could also increase the risk for knee osteoarthritis.

A new study increases our knowledge about the gut and the life of gut bacteria. The study shows, among other things, that changes in the gut environment have an impact on the composition and activity of gut bacteria. Ultimately, this may help explain why we all have different gut bacteria and probably also why we react differently to the same food.

Factors beyond carbohydrates have a substantial influence on blood glucose levels meaning current automated insulin delivery systems miss vital information required for glucose regulation, a new study has found.

Laboratory experiments with cancer cells reveal two ways in which tumors evade drugs designed to starve and kill them, a study shows.

A multicenter examination of data demonstrates that for patients with a body mass index at or above 70 kg/m2 metabolic and bariatric surgery is a potent intervention.

Fiber is something that most of us get far too little of. To change that, we need to actually enjoy eating it. Food researchers have now invented a 'disguise' that solves the problem of the dry and gritty mouth feel of fibers.

Salk scientists have tracked the flow of trans fats using mouse models to describe the molecular mechanisms that cause trans fats to promote atherosclerotic cardiovascular disease (ASCVD), explaining how industrially produced trans-unsaturated fatty acids in our food significantly promote ASCVD and encouraging lawmakers to impose regulations on the use of these fats in food. This new insight into the flow of fats through the body points to new therapeutic targets for mitigating diseases like ASCVD, non-alcoholic fatty liver disease, obesity, diabetes, peripheral neuropathy, and neurodegeneration.

Obesity causes insulin resistance by increasing activation of the sympathetic nervous system and the release of the stress hormone norepinephrine, according to a new study.

A new study has found that overnight eating may be putting night shift workers at higher risk of chronic health conditions.

Children who experienced sugar restrictions during their first 1,000 days after conception had up to 35% lower risk of developing type 2 diabetes and as much as 20% less risk of hypertension as adults. The researchers used contemporary data from the U.K. Biobank, a database of medical histories and genetic, lifestyle and other disease risk factors, to study the effect of those early-life sugar restrictions on health outcomes of adults conceived in the U.K. just before and after the end of wartime sugar rationing.

While the lockdowns associated with the COVID-19 pandemic led many families to eat more meals at home, they had an additional benefit: an increase in the quality of family time during those dinners, according to new research.

On June 5, United Natural Foods Inc. (UNFI, Providence, RI) suffered from a cyberattack, when the company noticed “unauthorized activity” on some of its information technology (IT) systems. According to a filing with the U.S. Securities and Exchange Commission, UNFI activated its incident response plan, which involved taking certain systems offline, impacting the company’s ability ...

The post UNFI Working to Restore Operations After Cyberattack appeared first on Vitamin Retailer Magazine.

A new double-blind, placebo-controlled study reveals daily supplementation with Pycnogenol French maritime pine bark extract from Horphag Research (Switzerland), reduces cellulite severity—a common skin condition most common in women, linked to dermal and vascular changes in the skin. The research found women who took Pycnogenol experienced measurable improvements in cellulite after 60 and 90 days. ...

The post New Study Shows Pycnogenol Alleviates Cellulite in Women appeared first on Vitamin Retailer Magazine.

On June 3, the Consumer Healthcare Products Association (CHPA) released the results of a new survey* which shows widespread consumer use and value in dietary supplements, and strong support for modernizing federal regulations. According to the survey, 92 percent of consumers agree supplements had a positive impact on their overall health, wellness and quality of ...

The post CHPA Survey Shows Strong Support for Dietary Supplement Reform appeared first on Vitamin Retailer Magazine.

On June 9, The Vitamin Shoppe (Secaucus, NJ) unveiled its Health & Wellness Report 2025, an in-depth, data-driven look at the evolving priorities, preferences and behaviors shaping the wellness industry. Now in its fourth year, the report combines proprietary sales and search insights from more than 600 retail locations, The Vitamin Shoppe website, industry-wide data ...

The post The Vitamin Shoppe Unveils 2025 Health & Wellness Trend Report appeared first on Vitamin Retailer Magazine.

On June 4, Dr. Bronner’s (Vista, CA) transferred ownership of its Magic All-One Chocolate line to Magic Chocolate Inc. Effective May 2025, the chocolate will now be known as “Magic Chocolate” and Dr. Bronner’s company name will no longer appear on the packaging. Founded by Swiss chocolatier Maestrani Schokoladen and Theo Chocolate Co-founder Joe Whinney, ...

The post Dr. Bronner’s Transfers Ownership of Chocolate Line appeared first on Vitamin Retailer Magazine.

NOW Sports (Bloomingdale, IL) often used branded, researched ingredients and posts links to the research on its website. “For example, our Pre-Workout Advanced Energy powder, with betaine, creatine, beta-alanine, carnitine, arginine and caffeine helps you stay focused and energized so you can train harder and longer,*” said Bryan Morin, sports brand manager at NOW. Muscle ...

The post [Extra! Extra!] A Scientifically Backed Pre-Workout appeared first on Vitamin Retailer Magazine.

The cognitive health market is a large one, and with all large supplement markets, there are plenty of ingredients that make big claims but are short on evidence. That’s why researchers at the Czech University of Life Sciences in Prague performed a literature review in 2022 to assess nootropic compounds’ efficacy. This literature review found ...

The post [Extra! Extra!] Cognitive Health for All Ages Continued appeared first on Vitamin Retailer Magazine.

iHerb (Irvine, CA) announced the launch of California Gold Nutrition Beauty, a new holistic self-care line made with premium ingredients to promote wellness from the inside out. The new line debuts with a targeted collection of hair multivitamins and clean hair care essentials. As iHerb’s largest and most trusted house brand, California Gold Nutrition now ...

The post iHerb Expands House Brand to Offer Beauty and Personal Care Products appeared first on Vitamin Retailer Magazine.

On May 15, supplement manufacturer Natura-Genics (Chino, CA) received a Good Manufacturing Practices (GMP) certification from UL Solutions to ensure consistent nutraceutical manufacturing practices, compliant with CFR 111 and to demonstrate continuous improvements in GMP standards. The company operates under licenses issued by the U.S. Food and Drug Administration (FDA), California Certified Organic Farmers (CCOF) ...

The post Natura-Genics Receives GMP Certification appeared first on Vitamin Retailer Magazine.

With a master’s degree in pharmaceutical chemistry and technology, Lorena Carboni specializes in the scientific and clinical aspects of natural ingredients, focusing on the one-carbon metabolites, including folate (5-MTHF), S-adenosylmethionine, glutathione and salidroside at Gnosis by Lesaffre. Over her 20-plus years in the nutraceutical and pharmaceutical industries, she proactively collaborates with universities and academic panels ...

The post Lorena Carboni, Senior Product Manager and Scientific Communications Expert, Gnosis by Lesaffre appeared first on Vitamin Retailer Magazine.

Updated Date: Thu, 15 Jul 2021 00:00:00 EDT

Learn about the warnings for sleep, skin and bodybuilding products that contain hidden drugs and other hidden ingredients.

Find answers to the most asked questions about medication health fraud and how to identify scams when buying products.

Learn about the warnings for pain and arthritis products that contain hidden drugs and other hidden ingredients.

Talk to friends and family about medication health fraud. Share FDA’s resources on ways to stay vigilant when buying products and supplements.

Health care providers can make personalized recommendations and help ensure that patients and consumers are accessing safe and effective treatments.

Many products claiming to help with health issues hide dangerous drug ingredients. Get informed about how to avoid contaminated products and their hidden ingredients.

The Food and Drug Administration is advising consumers not to purchase or use VITALITY, a product promoted and sold for sexual enhancement on https://www.zen-herbs.com and possibly in some retail stores.

The Food and Drug Administration is advising consumers not to purchase or use Special Edition Platinum 10K, a product promoted and sold for sexual enhancement on various websites and possibly in some retail stores.

The Food and Drug Administration is advising consumers not to purchase or use vROX, a product promoted and sold for sexual enhancement on various websites and possibly in some retail stores.

The Food and Drug Administration is advising consumers not to purchase or use ADVANCE KING, a product promoted and sold for joint pain on various websites, including www.naturistastore.com, and possibly in some retail stores.

The Food and Drug Administration is advising consumers not to purchase or use HimGo, a product promoted and sold for sexual enhancement on various websites, including ebay.com, and possibly in some retail stores.

The Food and Drug Administration is advising consumers not to purchase or use Kuka Flex Forte, a product promoted and sold for joint pain and arthritis on various websites, including https://botanical-be.com, and possibly in some retail stores.

The Food and Drug Administration is advising consumers not to purchase or use Reumo Flex, a product promoted and sold for joint pain and arthritis on various websites, including https://botanical-be.com, and possibly in some retail stores.

The Food and Drug Administration is advising consumers not to purchase or use Tapee Tea, a product promoted and sold for pain relief on www.tapeeteausa.com, www.tapeetea.com, and possibly in some retail stores.

The Food and Drug Administration is advising consumers not to purchase or use Fast-Act Rheuma Capsule, a product promoted and sold for joint pain and rheumatoid arthritis on various websites and possibly in some retail stores.

ITCHA XS may be harmful due to hidden drug ingredients

The Food and Drug Administration is advising consumers not to purchase or use Body Shape Weight Loss System, a product promoted for weight loss. This product was identified during an examination of imported goods.

The Food and Drug Administration is advising consumers not to purchase or use AK Forte, a product promoted and sold for joint pain and arthritis on various websites, including www.suprimoimports.com, and possibly in some retail stores.

FDA is advising consumers not to purchase or use Schwinnng, a product promoted and sold for sexual enhancement on various websites, including www.amazon.com, and possibly in some retail stores.

The Food and Drug Administration is advising consumers not to purchase or use TO THE MOON, a product promoted and sold for sexual enhancement on various websites, including www.amazon.com, and possibly in some retail stores.